Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI028284-02S1
Application #
3142688
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1990-04-01
Project End
1993-08-31
Budget Start
1990-04-01
Budget End
1990-08-31
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Wacher, V J; Liu, T; Roberts, J P et al. (1995) Time course of cyclosporine and ist motabolites in blood, liver and spleen of naive Lewis rats: comparison with preliminary data obtained in transplanted animals. Biopharm Drug Dispos 16:303-12
Osorio, R W; Ascher, N L; Melzer, J S et al. (1994) beta-2 Microglobulin gene disruption prolongs murine islet allograft survival in NOD mice. Transplant Proc 26:752
Osorio, R W; Ascher, N L; Melzer, J S et al. (1994) Enhancement of islet allograft survival in mice treated with MHC class I specific F(ab')2 alloantibody. Transplant Proc 26:749
Osorio, R W; Ascher, N L; Stock, P G (1994) Prolongation of in vivo mouse islet allograft survival by modulation of MHC class I antigen. Transplantation 57:783-8
Martinez, O M; Villanueva, J C; Lake, J et al. (1993) IL-2 and IL-5 gene expression in response to alloantigen in liver allograft recipients and in vitro. Transplantation 55:1159-66
Osorio, R W; Ascher, N L; Jaenisch, R et al. (1993) Isolation of functional MHC class I-deficient islet cells. Transplant Proc 25:968-9
Osorio, R W; Ascher, N L; Jaenisch, R et al. (1993) Major histocompatibility complex class I deficiency prolongs islet allograft survival. Diabetes 42:1520-7
Martinez, O M; Ascher, N L; Ferrell, L et al. (1993) Evidence for a nonclassical pathway of graft rejection involving interleukin 5 and eosinophils. Transplantation 55:909-18
Krams, S M; Ascher, N L; Martinez, O M (1993) New immunologic insights into mechanisms of allograft rejection. Gastroenterol Clin North Am 22:381-400
Freise, C E; Clemmings, S; Clemens, L E et al. (1991) Demonstration of local immunosuppression with methylprednisolone in the sponge matrix allograft model. Transplantation 52:318-25

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