Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI029103-06
Application #
2064817
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1990-07-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Mou, Zhirong; Muleme, Helen M; Liu, Dong et al. (2013) Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion. J Immunol 190:3380-9
Muleme, Helen M; Reguera, Rosa M; Berard, Alicia et al. (2009) Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease pathogenesis. J Immunol 183:8068-76
Kurahashi, Kiyoyasu; Sawa, Teiji; Ota, Maria et al. (2009) Depletion of phagocytes in the reticuloendothelial system causes increased inflammation and mortality in rabbits with Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol 296:L198-209
Frevert, Charles W; Goodman, Richard B; Kinsella, Michael G et al. (2002) Tissue-specific mechanisms control the retention of IL-8 in lungs and skin. J Immunol 168:3550-6
Kurdowska, A; Noble, J M; Steinberg, K P et al. (2001) Anti-interleukin 8 autoantibody: interleukin 8 complexes in the acute respiratory distress syndrome. Relationship between the complexes and clinical disease activity. Am J Respir Crit Care Med 163:463-8
Matute-Bello, G; Winn, R K; Jonas, M et al. (2001) Fas (CD95) induces alveolar epithelial cell apoptosis in vivo: implications for acute pulmonary inflammation. Am J Pathol 158:153-61
Sittipunt, C; Steinberg, K P; Ruzinski, J T et al. (2001) Nitric oxide and nitrotyrosine in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 163:503-10
Park, W Y; Goodman, R B; Steinberg, K P et al. (2001) Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 164:1896-903
Matute-Bello, G; Frevert, C W; Kajikawa, O et al. (2001) Septic shock and acute lung injury in rabbits with peritonitis: failure of the neutrophil response to localized infection. Am J Respir Crit Care Med 163:234-43
Martin, T R (2000) Recognition of bacterial endotoxin in the lungs. Am J Respir Cell Mol Biol 23:128-32

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