Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI029595-01S1
Application #
3144462
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1990-03-01
Project End
1995-02-28
Budget Start
1990-08-01
Budget End
1991-03-31
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Qu, X D; Lloyd, K C; Walsh, J H et al. (1996) Secretion of type II phospholipase A2 and cryptdin by rat small intestinal Paneth cells. Infect Immun 64:5161-5
Harwig, S S; Tan, L; Qu, X D et al. (1995) Bactericidal properties of murine intestinal phospholipase A2. J Clin Invest 95:603-10
Harwig, S S; Eisenhauer, P B; Chen, N P et al. (1995) Cryptdins: endogenous antibiotic peptides of small intestinal Paneth cells. Adv Exp Med Biol 371A:251-5
Kagan, B L; Ganz, T; Lehrer, R I (1994) Defensins: a family of antimicrobial and cytotoxic peptides. Toxicology 87:131-49
Lehrer, R I; Lichtenstein, A K; Ganz, T (1993) Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol 11:105-28
Harwig, S S; Chen, N P; Park, A S et al. (1993) Purification of cysteine-rich bioactive peptides from leukocytes by continuous acid-urea-polyacrylamide gel electrophoresis. Anal Biochem 208:382-6
Couto, M A; Harwig, S S; Lehrer, R I (1993) Selective inhibition of microbial serine proteases by eNAP-2, an antimicrobial peptide from equine neutrophils. Infect Immun 61:2991-4
Hiemstra, P S; Eisenhauer, P B; Harwig, S S et al. (1993) Antimicrobial proteins of murine macrophages. Infect Immun 61:3038-46
Selsted, M E; Miller, S I; Henschen, A H et al. (1992) Enteric defensins: antibiotic peptide components of intestinal host defense. J Cell Biol 118:929-36
Eisenhauer, P B; Harwig, S S; Lehrer, R I (1992) Cryptdins: antimicrobial defensins of the murine small intestine. Infect Immun 60:3556-65

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