Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI030006-04A3
Application #
2065364
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1991-09-30
Project End
2001-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University of New York at Buffalo
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Schilling, Birgit; Gibson, Bradford W; Filiatrault, Melanie et al. (2002) Characterization of lipooligosaccharides from Haemophilus ducreyi containing polylactosamine repeats. J Am Soc Mass Spectrom 13:724-34
Tullius, Michael V; Phillips, Nancy J; Scheffler, N Karoline et al. (2002) The lbgAB gene cluster of Haemophilus ducreyi encodes a beta-1,4-galactosyltransferase and an alpha-1,6-DD-heptosyltransferase involved in lipooligosaccharide biosynthesis. Infect Immun 70:2853-61
Filiatrault, M J; Munson Jr, R S; Campagnari, A A (2001) Genetic analysis of a pyocin-resistant lipooligosaccharide (LOS) mutant of Haemophilus ducreyi: restoration of full-length LOS restores pyocin sensitivity. J Bacteriol 183:5756-61
Young, R S; Filiatrault, M J; Fortney, K R et al. (2001) Haemophilus ducreyi lipooligosaccharide mutant defective in expression of beta-1,4-glucosyltransferase is virulent in humans. Infect Immun 69:4180-4
Filiatrault, M J; Gibson, B W; Schilling, B et al. (2000) Construction and characterization of Haemophilus ducreyi lipooligosaccharide (LOS) mutants defective in expression of heptosyltransferase III and beta1,4-glucosyltransferase: identification of LOS glycoforms containing lactosamine repeats. Infect Immun 68:3352-61
Palmer, K L; Thornton, A C; Fortney, K R et al. (1998) Evaluation of an isogenic hemolysin-deficient mutant in the human model of Haemophilus ducreyi infection. J Infect Dis 178:191-9
Gibson, B W; Campagnari, A A; Melaugh, W et al. (1997) Characterization of a transposon Tn916-generated mutant of Haemophilus ducreyi 35000 defective in lipooligosaccharide biosynthesis. J Bacteriol 179:5062-71
Spinola, S M; Orazi, A; Arno, J N et al. (1996) Haemophilus ducreyi elicits a cutaneous infiltrate of CD4 cells during experimental human infection. J Infect Dis 173:394-402
Melaugh, W; Campagnari, A A; Gibson, B W (1996) The lipooligosaccharides of Haemophilus ducreyi are highly sialylated. J Bacteriol 178:564-70
Spinola, S M; Wild, L M; Apicella, M A et al. (1994) Experimental human infection with Haemophilus ducreyi. J Infect Dis 169:1146-50

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