Antigen Processing Genes and Cell Biology

Pious, Donald A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI030527-05
• Application #: 2065676
• Study Section: Experimental Immunology Study Section (EI)
• Project Start: 1991-01-01
• Project End: 1996-12-31
• Budget Start: 1995-01-01
• Budget End: 1996-12-31
• Support Year: 5
• Fiscal Year: 1995

Institution

• Name: University of Washington
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 135646524
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98195

Publications

Muczynski, Kimberly A; Ekle, David M; Coder, David M et al. (2003) Normal human kidney HLA-DR-expressing renal microvascular endothelial cells: characterization, isolation, and regulation of MHC class II expression. J Am Soc Nephrol 14:1336-48

Muczynski, K A; Cotner, T; Anderson, S K (2001) Unusual expression of human lymphocyte antigen class II in normal renal microvascular endothelium. Kidney Int 59:488-97

Muczynski, K A; Anderson, S K; Pious, D (1998) Discoordinate surface expression of IFN-gamma-induced HLA class II proteins in nonprofessional antigen-presenting cells with absence of DM and class II colocalization. J Immunol 160:3207-16

Fling, S P; Rak, J; Muczynski, K A et al. (1997) Novel mutants define genes required for the expression of human histocompatibility leukocyte antigen DM: evidence for loci on human chromosome 6p. J Exp Med 186:1469-80

Monji, T; Pious, D (1997) Exogenously provided peptides fail to complex with intracellular class II molecules for presentation by antigen-presenting cells. J Immunol 158:3155-64

Monji, T; McCormack, A L; Yates 3rd, J R et al. (1994) Invariant-cognate peptide exchange restores class II dimer stability in HLA-DM mutants. J Immunol 153:4468-77

Mellins, E; Kempin, S; Smith, L et al. (1991) A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex. J Exp Med 174:1607-15