Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI030575-06A1
Application #
2065737
Study Section
Immunobiology Study Section (IMB)
Project Start
1991-01-01
Project End
2001-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206
Kovacs, Birgit; Parry, Richard V; Ma, Zhengyu et al. (2005) Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells. J Immunol 175:7848-54
Feuerstein, Nili; DeSimone, Dennis C; Eisenberg, Robert A et al. (2004) Chronic graft-versus-host reaction is associated with a decrease in Ig light chain receptor editing in bone marrow self-reactive B cells. Eur J Immunol 34:1361-70
Kovacs, Birgit; Maus, Marcela V; Riley, James L et al. (2002) Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation. Proc Natl Acad Sci U S A 99:15006-11
Marschner, Susanne; Hunig, Thomas; Cambier, John C et al. (2002) Ligation of human CD4 interferes with antigen-induced activation of primary T cells. Immunol Lett 82:131-9
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Angkachatchai, V; Finkel, T H (1999) ADP-ribosylation of rho by C3 ribosyltransferase inhibits IL-2 production and sustained calcium influx in activated T cells. J Immunol 163:3819-25
Rozdzial, M M; Pleiman, C M; Cambier, J C et al. (1998) pp56Lck mediates TCR zeta-chain binding to the microfilament cytoskeleton. J Immunol 161:5491-9
Rozdzial, M M; Malissen, B; Finkel, T H (1995) Tyrosine-phosphorylated T cell receptor zeta chain associates with the actin cytoskeleton upon activation of mature T lymphocytes. Immunity 3:623-33
Rozdzial, M M; Kubo, R T; Turner, S L et al. (1994) Developmental regulation of the TCR zeta-chain. Differential expression and tyrosine phosphorylation of the TCR zeta-chain in resting immature and mature T lymphocytes. J Immunol 153:1563-80
Paterson, R K; Burkly, L C; Kurahara, D K et al. (1994) Thymic development in human CD4 transgenic mice. Positive selection occurs after commitment to the CD8 lineage. J Immunol 153:3491-503

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