Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI030628-02S1
Application #
3145694
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1991-07-01
Project End
1996-04-30
Budget Start
1993-04-01
Budget End
1993-04-30
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Baker, C J; Paoletti, L C; Wessels, M R et al. (1999) Safety and immunogenicity of capsular polysaccharide-tetanus toxoid conjugate vaccines for group B streptococcal types Ia and Ib. J Infect Dis 179:142-50
Paoletti, L C; Pinel, J; Rodewald, A K et al. (1997) Therapeutic potential of human antisera to group B streptococcal glycoconjugate vaccines in neonatal mice. J Infect Dis 175:1237-9
Guttormsen, H K; Baker, C J; Edwards, M S et al. (1996) Quantitative determination of antibodies to type III group B streptococcal polysaccharide. J Infect Dis 173:142-50
Kasper, D L; Paoletti, L C; Wessels, M R et al. (1996) Immune response to type III group B streptococcal polysaccharide-tetanus toxoid conjugate vaccine. J Clin Invest 98:2308-14
Wessels, M R; Paoletti, L C; Pinel, J et al. (1995) Immunogenicity and protective activity in animals of a type V group B streptococcal polysaccharide-tetanus toxoid conjugate vaccine. J Infect Dis 171:879-84
Kasper, D L (1995) Designer vaccines to prevent infections due to group B Streptococcus. Proc Assoc Am Physicians 107:369-73
Paoletti, L C; Wessels, M R; Rodewald, A K et al. (1994) Neonatal mouse protection against infection with multiple group B streptococcal (GBS) serotypes by maternal immunization with a tetravalent GBS polysaccharide-tetanus toxoid conjugate vaccine. Infect Immun 62:3236-43
Wessels, M R; Paoletti, L C; Rodewald, A K et al. (1993) Stimulation of protective antibodies against type Ia and Ib group B streptococci by a type Ia polysaccharide-tetanus toxoid conjugate vaccine. Infect Immun 61:4760-6
Paoletti, L C; Wessels, M R; Michon, F et al. (1992) Group B Streptococcus type II polysaccharide-tetanus toxoid conjugate vaccine. Infect Immun 60:4009-14