Effect of Borrelia on Endothelial Cells and Leukocytes

Furie, Martha B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI031086-03
• Application #: 2066102
• Study Section: Tropical Medicine and Parasitology Study Section (TMP)
• Project Start: 1993-05-01
• Project End: 1997-04-30
• Budget Start: 1995-05-01
• Budget End: 1997-04-30
• Support Year: 3
• Fiscal Year: 1995

Institution

• Name: State University New York Stony Brook
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 804878247
• City: Stony Brook
• State: NY
• Country: United States
• Zip Code: 11794

Publications

Burns, M J; Sellati, T J; Teng, E I et al. (1997) Production of interleukin-8 (IL-8) by cultured endothelial cells in response to Borrelia burgdorferi occurs independently of secreted [corrected] IL-1 and tumor necrosis factor alpha and is required for subsequent transendothelial migration of neutrophil Infect Immun 65:1217-22

Sellati, T J; Abrescia, L D; Radolf, J D et al. (1996) Outer surface lipoproteins of Borrelia burgdorferi activate vascular endothelium in vitro. Infect Immun 64:3180-7

Sellati, T J; Burns, M J; Ficazzola, M A et al. (1995) Borrelia burgdorferi upregulates expression of adhesion molecules on endothelial cells and promotes transendothelial migration of neutrophils in vitro. Infect Immun 63:4439-47

Coleman, J L; Sellati, T J; Testa, J E et al. (1995) Borrelia burgdorferi binds plasminogen, resulting in enhanced penetration of endothelial monolayers. Infect Immun 63:2478-84