Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI031453-02
Application #
2003687
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1995-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sidney Kimmel Cancer Center
Department
Type
DUNS #
City
San Diego
State
CA
Country
United States
Zip Code
92121
Jung, Barbara; Barbier, Valerie; Brickner, Howard et al. (2005) Mechanisms of sulindac-induced apoptosis and cell cycle arrest. Cancer Lett 219:15-25
Pennaneach, V; Salles-Passador, I; Munshi, A et al. (2001) The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner. Mol Cell 7:715-27
Boulaire, J; Fotedar, A; Fotedar, R (2000) The functions of the cdk-cyclin kinase inhibitor p21WAF1. Pathol Biol (Paris) 48:190-202
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Fotedar, R; Brickner, H; Saadatmandi, N et al. (1999) Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells. Oncogene 18:3652-8
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Rousseau, D; Cannella, D; Boulaire, J et al. (1999) Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway. Oncogene 18:4313-25
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Fotedar, R; Fitzgerald, P; Rousselle, T et al. (1996) p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity. Oncogene 12:2155-64
Fotedar, R; Mossi, R; Fitzgerald, P et al. (1996) A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells. EMBO J 15:4423-33

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