Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI031946-02
Application #
2066871
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1995-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Surgery
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Welling, Theodore H; Lu, Guanyi; Csencsits, Keri et al. (2008) Regulation of alloimmune Th1 responses by the cyclin-dependent kinase inhibitor p21 following transplantation. Surgery 143:394-403
Brown, David L; Bishop, D Keith; Wood, Sherri Y et al. (2006) Short-term anti-CD40 ligand costimulatory blockade induces tolerance to peripheral nerve allografts, resulting in improved skeletal muscle function. Plast Reconstr Surg 117:2250-8
Csencsits, K; Wood, S C; Lu, G et al. (2006) Transforming growth factor beta-induced connective tissue growth factor and chronic allograft rejection. Am J Transplant 6:959-66
Rovak, Jason M; Bishop, D Keith; Boxer, Leslie K et al. (2005) Peripheral nerve transplantation: the role of chemical acellularization in eliminating allograft antigenicity. J Reconstr Microsurg 21:207-13
Csencsits, Keri; Wood, Sherri Chan; Lu, Guanyi et al. (2005) Transforming growth factor-beta1 gene transfer is associated with the development of regulatory cells. Am J Transplant 5:2378-84
Nathan, Meera J; Mold, Jeffrey E; Wood, Sherri C et al. (2004) Requirement for donor and recipient CD40 expression in cardiac allograft rejection: induction of Th1 responses and influence of donor-derived dendritic cells. J Immunol 172:6626-33
Csencsits, Keri L; Bishop, D Keith (2003) Contrasting alloreactive CD4+ and CD8+ T cells: there's more to it than MHC restriction. Am J Transplant 3:107-15
Nathan, Meera J; Yin, Dengping; Eichwald, Ernst J et al. (2002) The immunobiology of inductive anti-CD40L therapy in transplantation: allograft acceptance is not dependent upon the deletion of graft-reactive T cells. Am J Transplant 2:323-32
Chan, S Y; Goodman, R E; Szmuszkovicz, J R et al. (2000) DNA-liposome versus adenoviral mediated gene transfer of transforming growth factor beta1 in vascularized cardiac allografts: differential sensitivity of CD4+ and CD8+ T cells to transforming growth factor beta1. Transplantation 70:1292-301
DeBruyne, L A; Li, K; Bishop, D K et al. (2000) Gene transfer of virally encoded chemokine antagonists vMIP-II and MC148 prolongs cardiac allograft survival and inhibits donor-specific immunity. Gene Ther 7:575-82

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