Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032560-05
Application #
2067461
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1992-09-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1998-04-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Henry M. Jackson Fdn for the Adv Mil/Med
Department
Type
DUNS #
City
Rockville
State
MD
Country
United States
Zip Code
20817
Horwitz, B H; Zelazowski, P; Shen, Y et al. (1999) The p65 subunit of NF-kappa B is redundant with p50 during B cell proliferative responses, and is required for germline CH transcription and class switching to IgG3. J Immunol 162:1941-6
Vos, Q; Snapper, C M; Mond, J J (1999) Heterogeneity in the ability of cytotoxic murine NK cell clones to enhance Ig secretion in vitro. Int Immunol 11:159-68
Vos, Q; Ortaldo, J R; Conan-Cibotti, M et al. (1998) Phenotypic and functional characterization of a panel of cytotoxic murine NK cell clones that are heterogeneous in their enhancement of Ig secretion in vitro. Int Immunol 10:1093-101
Snapper, C M; Rosas, F R; Kehry, M R et al. (1997) Neisserial porins may provide critical second signals to polysaccharide-activated murine B cells for induction of immunoglobulin secretion. Infect Immun 65:3203-8
Zelazowski, P; Max, E E; Kehry, M R et al. (1997) Regulation of Ku expression in normal murine B cells by stimuli that promote switch recombination. J Immunol 159:2559-62
Zelazowski, P; Carrasco, D; Rosas, F R et al. (1997) B cells genetically deficient in the c-Rel transactivation domain have selective defects in germline CH transcription and Ig class switching. J Immunol 159:3133-9
Snapper, C M; Rosas, F R; Moorman, M A et al. (1997) Restoration of T cell-independent type 2 induction of Ig secretion by neonatal B cells in vitro. J Immunol 158:2731-5
Shparago, N; Zelazowski, P; Jin, L et al. (1996) IL-10 selectively regulates murine Ig isotype switching. Int Immunol 8:781-90
Snapper, C M; Rosas, F R; Zelazowski, P et al. (1996) B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching. J Exp Med 184:1537-41
Snapper, C M; Rosas, F; Moorman, M A et al. (1996) IFN-gamma is a potent inducer of Ig secretion by sort-purified murine B cells activated through the mIg, but not the CD40, signaling pathway. Int Immunol 8:877-85

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