Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032784-06
Application #
2067691
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1991-09-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Nopponpunth, V; Sirawaraporn, W; Greene, P J et al. (1999) Cloning and expression of Mycobacterium tuberculosis and Mycobacterium leprae dihydropteroate synthase in Escherichia coli. J Bacteriol 181:6814-21
Trujillo, M; Duncan, R; Santi, D V (1997) Construction of a homodimeric dihydrofolate reductase-thymidylate synthase bifunctional enzyme. Protein Eng 10:567-73
Trujillo, M; Donald, R G; Roos, D S et al. (1996) Heterologous expression and characterization of the bifunctional dihydrofolate reductase-thymidylate synthase enzyme of Toxoplasma gondii. Biochemistry 35:6366-74
Livi, L L; Edman, U; Schneider, G P et al. (1994) Cloning, expression and characterization of thymidylate synthase from Cryptococcus neoformans. Gene 150:221-6
Margosiak, S A; Appleman, J R; Santi, D V et al. (1993) Dihydrofolate reductase from the pathogenic fungus Pneumocystis carinii: catalytic properties and interaction with antifolates. Arch Biochem Biophys 305:499-508
Santi, D V; Edman, U; Minkin, S et al. (1991) Purification and characterization of recombinant Pneumocystis carinii thymidylate synthase. Protein Expr Purif 2:350-4