Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032871-05
Application #
2067745
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1992-05-15
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Ferris, R L; Hall, C; Sipsas, N V et al. (1999) Processing of HIV-1 envelope glycoprotein for class I-restricted recognition: dependence on TAP1/2 and mechanisms for cytosolic localization. J Immunol 162:1324-32
Ray, S C; Lubaki, N; Dhruva, B R et al. (1998) Autologous strain-specific cytolytic T lymphocyte responses directed against human immunodeficiency virus type 1 Env. AIDS Res Hum Retroviruses 14:3-13
McElrath, M J; Siliciano, R F; Weinhold, K J (1997) HIV type 1 vaccine-induced cytotoxic T cell responses in phase I clinical trials: detection, characterization, and quantitation. AIDS Res Hum Retroviruses 13:211-6
Lubaki, N M; Ray, S C; Dhruva, B et al. (1997) Characterization of a polyclonal cytolytic T lymphocyte response to human immunodeficiency virus in persons without clinical progression. J Infect Dis 175:1360-7
Liu, A Y; Torchia, B S; Migeon, B R et al. (1997) The human NTT gene: identification of a novel 17-kb noncoding nuclear RNA expressed in activated CD4+ T cells. Genomics 39:171-84
Ferris, R L; Buck, C; Hammond, S A et al. (1996) Class I-restricted presentation of an HIV-1 gp41 epitope containing an N-linked glycosylation site. Implications for the mechanism of processing of viral envelope proteins. J Immunol 156:834-40
Egan, M A; Pavlat, W A; Tartaglia, J et al. (1995) Induction of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic T lymphocyte responses in seronegative adults by a nonreplicating, host-range-restricted canarypox vector (ALVAC) carrying the HIV-1MN env gene. J Infect Dis 171:1623-7
Hammond, S A; Johnson, R P; Kalams, S A et al. (1995) An epitope-selective, transporter associated with antigen presentation (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen-processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8+ CTL. J Immunol 154:6140-56
Miskovsky, E P; Liu, A Y; Pavlat, W et al. (1994) Studies of the mechanism of cytolysis by HIV-1-specific CD4+ human CTL clones induced by candidate AIDS vaccines. J Immunol 153:2787-99
Lubaki, M N; Egan, M A; Siliciano, R F et al. (1994) A novel method for detection and ex vivo expansion of HIV type 1-specific cytolytic T lymphocytes. AIDS Res Hum Retroviruses 10:1427-31

Showing the most recent 10 out of 13 publications