Triplex Forming Oligonucleotides Targeted Against HIV 1

Hogan, Michael E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI032894-05
• Application #: 2067787
• Study Section: AIDS and Related Research Study Section 4 (ARRD)
• Project Start: 1992-03-01
• Project End: 1998-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: Baylor College of Medicine
• Department: Other Health Professions
• Type: Schools of Medicine
• DUNS #: 074615394
• City: Houston
• State: TX
• Country: United States
• Zip Code: 77030

Publications

Jing, N; Hogan, M E (1998) Structure-activity of tetrad-forming oligonucleotides as a potent anti-HIV therapeutic drug. J Biol Chem 273:34992-9

Ojwang, J O; Lewis, A F; Revankar, G R et al. (1997) Sequence-specific inhibition of the tumor necrosis factor-alpha receptor I gene by oligodeoxynucleotides containing N7 modified 2'-deoxyguanosine. Antisense Nucleic Acid Drug Dev 7:447-59

Gee, J E; Revankar, G R; Rao, T S et al. (1995) Triplex formation at the rat neu gene utilizing imidazole and 2'-deoxy-6-thioguanosine base substitutions. Biochemistry 34:2042-8