Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI033031-03
Application #
2068001
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1992-12-01
Project End
1997-09-29
Budget Start
1994-12-01
Budget End
1997-09-29
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Purdue University
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Liu, H; Cohen, D E; Pidgeon, C (1997) Single step purification of rat liver aldolase using immobilized artificial membrane chromatography. J Chromatogr B Biomed Sci Appl 703:53-62
Bernal, C; Pidgeon, C (1996) Affinity purification of phospholipase A2 on immobilized artificial membranes containing and lacking the glycerol backbone. J Chromatogr A 731:139-51
Ong, S; Liu, H; Pidgeon, C (1996) Immobilized-artificial-membrane chromatography: measurements of membrane partition coefficient and predicting drug membrane permeability. J Chromatogr A 728:113-28
Pidgeon, C; Cai, S J; Bernal, C (1996) Mobile phase effects on membrane protein elution during immobilized artificial membrane chromatography. J Chromatogr A 721:213-30
Pidgeon, C; Ong, S; Liu, H et al. (1995) IAM chromatography: an in vitro screen for predicting drug membrane permeability. J Med Chem 38:590-4
Ong, S; Pidgeon, C (1995) Thermodynamics of solute partitioning into immobilized artificial membranes. Anal Chem 67:2119-28
Ong, S; Liu, H; Qiu, X et al. (1995) Membrane partition coefficients chromatographically measured using immobilized artificial membrane surfaces. Anal Chem 67:755-62
Cai, S J; McAndrew, R S; Leonard, B P et al. (1995) Rapid purification of cotton seed membrane-bound N-acylphosphatidylethanolamine synthase by immobilized artificial membrane chromatography. J Chromatogr A 696:49-62
Liu, H; Ong, S; Glunz, L et al. (1995) Predicting drug-membrane interactions by HPLC: structural requirements of chromatographic surfaces. Anal Chem 67:3550-7
Qiu, X; Pidgeon, C (1994) Membrane properties of antiviral phospholipids containing heteroatoms in the acyl chains. Biochemistry 33:960-72

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