Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI033100-05
Application #
2068089
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1992-07-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Womer, Karl L; Magee, Colm C; Najafian, Nader et al. (2008) A pilot study on the immunological effects of oral administration of donor major histocompatibility complex class II peptides in renal transplant recipients. Clin Transplant 22:754-9
Salama, Alan D; Najafian, Nader; Clarkson, Michael R et al. (2003) Regulatory CD25+ T cells in human kidney transplant recipients. J Am Soc Nephrol 14:1643-51
Kist-van Holthe, Joana E; Gasser, Martin; Womer, Karl et al. (2002) Regulatory functions of alloreactive Th2 clones in human renal transplant recipients. Kidney Int 62:627-31
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Najafian, Nader; Salama, Alan D; Fedoseyeva, Eugenia V et al. (2002) Enzyme-linked immunosorbent spot assay analysis of peripheral blood lymphocyte reactivity to donor HLA-DR peptides: potential novel assay for prediction of outcomes for renal transplant recipients. J Am Soc Nephrol 13:252-9
Frank, M H; Denton, M D; Alexander, S I et al. (2001) Specific MDR1 P-glycoprotein blockade inhibits human alloimmune T cell activation in vitro. J Immunol 166:2451-9
Stadlbauer, T H; Schaub, M; Magee, C C et al. (2000) Intrathymic immunomodulation in sensitized rat recipients of cardiac allografts: requirements for allorecognition pathways. J Heart Lung Transplant 19:566-75
Onodera, K; Chandraker, A; Volk, H D et al. (1999) Distinct tolerance pathways in sensitized allograft recipients after selective blockade of activation signal 1 or signal 2. Transplantation 68:288-93
Murphy, B; Magee, C C; Alexander, S I et al. (1999) Inhibition of allorecognition by a human class II MHC-derived peptide through the induction of apoptosis. J Clin Invest 103:859-67
Lara-Marquez, M L; Deykin, A; Krinzman, S et al. (1998) Analysis of T-cell activation after bronchial allergen challenge in patients with atopic asthma. J Allergy Clin Immunol 101:699-708

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