Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI033470-03
Application #
2068502
Study Section
Immunobiology Study Section (IMB)
Project Start
1994-05-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206
Huber, S A; Sakkinen, P; David, C et al. (2001) T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemia. Circulation 103:2610-6
Desbarats, J; Stone, J E; Lin, L et al. (2000) Rapid early onset lymphocyte cell death in mice resistant, but not susceptible to Leishmania major infection. Apoptosis 5:189-96
Huber, S A; Kupperman, J; Newell, M K (1999) Estradiol prevents and testosterone promotes Fas-dependent apoptosis in CD4+ Th2 cells by altering Bcl 2 expression. Lupus 8:384-7
Huber, S A; Kupperman, J; Newell, M K (1999) Hormonal regulation of CD4(+) T-cell responses in coxsackievirus B3-induced myocarditis in mice. J Virol 73:4689-95
Chien, M M; Zahradka, K E; Newell, M K et al. (1999) Fas-induced B cell apoptosis requires an increase in free cytosolic magnesium as an early event. J Biol Chem 274:7059-66
Desbarats, J; Duke, R C; Newell, M K (1998) Newly discovered role for Fas ligand in the cell-cycle arrest of CD4+ T cells. Nat Med 4:1377-82
Bhushan, A; Kupperman, J L; Stone, J E et al. (1998) Drug resistance results in alterations in expression of immune recognition molecules and failure to express Fas (CD95). Immunol Cell Biol 76:350-6
Folzenlogen, D; Hofer, M F; Leung, D Y et al. (1997) Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients. Clin Immunol Immunopathol 83:199-204
Desbarats, J; Freed, J H; Campbell, P A et al. (1996) Fas (CD95) expression and death-mediating function are induced by CD4 cross-linking on CD4+ T cells. Proc Natl Acad Sci U S A 93:11014-8
Wagner Jr, D H; Hagman, J; Linsley, P S et al. (1996) Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2. J Exp Med 184:1631-8