Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI033511-04
Application #
2068562
Study Section
Special Emphasis Panel (SRC (42))
Project Start
1993-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Tennessee Knoxville
Department
Microbiology/Immun/Virology
Type
Schools of Veterinary Medicine
DUNS #
City
Knoxville
State
TN
Country
United States
Zip Code
37996
Davis, I A; Rouse, B T (2000) Identification of select lymphocyte homing molecules and vascular addressins in lymphotoxin-alpha deficient mice. Lab Anim 34:111-4
Rouse, B T; Nair, S; Rouse, R J et al. (1998) DNA vaccines and immunity to herpes simplex virus. Curr Top Microbiol Immunol 226:69-78
Kuklin, N A; Daheshia, M; Marconi, P C et al. (1998) Modulation of mucosal and systemic immunity by enteric administration of nonreplicating herpes simplex virus expressing cytokines. Virology 240:245-53
Davis, I A; Rouse, B T (1998) Immune responsiveness of lymphotoxin-alpha-deficient mice: two reconstitution models. Cell Immunol 189:116-24
Chun, S; Daheshia, M; Kuklin, N A et al. (1998) Modulation of viral immunoinflammatory responses with cytokine DNA administered by different routes. J Virol 72:5545-51
Kuklin, N A; Daheshia, M; Chun, S et al. (1998) Role of mucosal immunity in herpes simplex virus infection. J Immunol 160:5998-6003
Davis, I A; Knight, K A; Rouse, B T (1998) The spleen and organized lymph nodes are not essential for the development of gut-induced mucosal immune responses in lymphotoxin-alpha deficient mice. Clin Immunol Immunopathol 89:150-9
Kuklin, N A; Daheshia, M; Chun, S et al. (1998) Immunomodulation by mucosal gene transfer using TGF-beta DNA. J Clin Invest 102:438-44
Manickan, E; Karem, K L; Rouse, B T (1997) DNA vaccines -- a modern gimmick or a boon to vaccinology? Crit Rev Immunol 17:139-54
Kuklin, N; Daheshia, M; Karem, K et al. (1997) Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization. J Virol 71:3138-45

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