Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI033614-04
Application #
2068688
Study Section
Immunobiology Study Section (IMB)
Project Start
1993-07-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Pathology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Zhou, Zemin; Reyes-Vargas, Eduardo; Escobar, Hernando et al. (2017) Peptidomic analysis of type 1 diabetes associated HLA-DQ molecules and the impact of HLA-DM on peptide repertoire editing. Eur J Immunol 47:314-326
Zhou, Zemin; Reyes-Vargas, Eduardo; Escobar, Hernando et al. (2016) Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptides. Eur J Immunol 46:834-45
Chen, Lili; Reyes-Vargas, Eduardo; Dai, Hu et al. (2014) Expression of the mouse MHC class Ib H2-T11 gene product, a paralog of H2-T23 (Qa-1) with shared peptide-binding specificity. J Immunol 193:1427-39
Gu, Yapeng; Jensen, Peter E; Chen, Xinjian (2013) Immunodeficiency and autoimmunity in H2-O-deficient mice. J Immunol 190:126-37
Chen, Lili; Jay, David C; Fairbanks, Jared D et al. (2011) An MHC class Ib-restricted CD8+ T cell response to lymphocytic choriomeningitis virus. J Immunol 187:6463-72
Zhou, Zemin; Callaway, Kari A; Weber, Dominique A et al. (2009) Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes. J Immunol 183:4187-91
Swanson 2nd, Phillip A; Pack, Christopher D; Hadley, Annette et al. (2008) An MHC class Ib-restricted CD8 T cell response confers antiviral immunity. J Exp Med 205:1647-57
Escobar, Hernando; Crockett, David K; Reyes-Vargas, Eduardo et al. (2008) Large scale mass spectrometric profiling of peptides eluted from HLA molecules reveals N-terminal-extended peptide motifs. J Immunol 181:4874-82
Jay, David C; Reed-Loisel, Lisa M; Jensen, Peter E (2008) Polyclonal MHC Ib-restricted CD8+ T cells undergo homeostatic expansion in the absence of conventional MHC-restricted T cells. J Immunol 180:2805-14
Chen, Xinjian; Reed-Loisel, Lisa M; Karlsson, Lars et al. (2006) H2-O expression in primary dendritic cells. J Immunol 176:3548-56

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