Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034065-03
Application #
2069155
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1994-09-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Emory University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322

  Publications

Zakharova, Maria; Ziegler, H Kirk (2005) Paradoxical anti-inflammatory actions of TNF-alpha: inhibition of IL-12 and IL-23 via TNF receptor 1 in macrophages and dendritic cells. J Immunol 175:5024-33
Freeman, Molly M; Ziegler, H Kirk (2005) Simultaneous Th1-type cytokine expression is a signature of peritoneal CD4+ lymphocytes responding to infection with Listeria monocytogenes. J Immunol 175:394-403
Skeen, M J; Rix, E P; Freeman, M M et al. (2001) Exaggerated proinflammatory and Th1 responses in the absence of gamma/delta T cells after infection with Listeria monocytogenes. Infect Immun 69:7213-23
Zirk, N M; Hashmi, S F; Ziegler, H K (1999) The polysaccharide portion of lipopolysaccharide regulates antigen-specific T-cell activation via effects on macrophage-mediated antigen processing. Infect Immun 67:319-26
Miller, M A; Skeen, M J; Ziegler, H K (1998) Long-lived protective immunity to Listeria is conferred by immunization with particulate or soluble listerial antigen preparations coadministered with IL-12. Cell Immunol 184:92-104
Miller, M A; Skeen, M J; Ziegler, H K (1997) A synthetic peptide administered with IL-12 elicits immunity to Listeria monocytogenes. J Immunol 159:3675-9
Hiltbold, E M; Ziegler, H K (1996) Interferon-gamma and interleukin-10 have cross-regulatory roles in modulating the class I and class II MHC-mediated presentation of epitopes of Listeria monocytogenes by infected macrophages. J Interferon Cytokine Res 16:547-54
Miller, M A; Skeen, M J; Ziegler, H K (1995) Nonviable bacterial antigens administered with IL-12 generate antigen-specific T cell responses and protective immunity against Listeria monocytogenes. J Immunol 155:4817-28