Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034242-04
Application #
2069337
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1993-09-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Vincent, M J; Melsen, L R; Martin, A S et al. (1999) Intracellular interaction of simian immunodeficiency virus Gag and Env proteins. J Virol 73:8138-44
Vincent, M J; Martin, A S; Compans, R W (1998) Function of the KKXX motif in endoplasmic reticulum retrieval of a transmembrane protein depends on the length and structure of the cytoplasmic domain. J Biol Chem 273:950-6
Ball, J M; Mulligan, M J; Compans, R W (1997) Basolateral sorting of the HIV type 2 and SIV envelope glycoproteins in polarized epithelial cells: role of the cytoplasmic domain. AIDS Res Hum Retroviruses 13:665-75
Yang, C; Compans, R W (1997) Analysis of the murine leukemia virus R peptide: delineation of the molecular determinants which are important for its fusion inhibition activity. J Virol 71:8490-6
Yang, C; Compans, R W (1996) Analysis of the cell fusion activities of chimeric simian immunodeficiency virus-murine leukemia virus envelope proteins: inhibitory effects of the R peptide. J Virol 70:248-54
Vzorov, A N; Compans, R W (1996) Assembly and release of SIV env proteins with full-length or truncated cytoplasmic domains. Virology 221:22-33
Yang, C; Spies, C P; Compans, R W (1995) The human and simian immunodeficiency virus envelope glycoprotein transmembrane subunits are palmitoylated. Proc Natl Acad Sci U S A 92:9871-5
Yamshchikov, G V; Ritter, G D; Vey, M et al. (1995) Assembly of SIV virus-like particles containing envelope proteins using a baculovirus expression system. Virology 214:50-8
Spies, C P; Ritter Jr, G D; Mulligan, M J et al. (1994) Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein alters the conformation of the external domain. J Virol 68:585-91
Spies, C P; Compans, R W (1994) Effects of cytoplasmic domain length on cell surface expression and syncytium-forming capacity of the simian immunodeficiency virus envelope glycoprotein. Virology 203:8-19