Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034530-09
Application #
6779874
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Schmitt, Clare K
Project Start
1995-08-01
Project End
2006-05-31
Budget Start
2004-06-01
Budget End
2006-05-31
Support Year
9
Fiscal Year
2004
Total Cost
$218,250
Indirect Cost
Name
Texas A&M University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
141582986
City
College Station
State
TX
Country
United States
Zip Code
77845
Tesh, Vernon L (2012) The induction of apoptosis by Shiga toxins and ricin. Curr Top Microbiol Immunol 357:137-78
Leyva-Illades, Dinorah; Cherla, Rama P; Lee, Moo-Seung et al. (2012) Regulation of cytokine and chemokine expression by the ribotoxic stress response elicited by Shiga toxin type 1 in human macrophage-like THP-1 cells. Infect Immun 80:2109-20
Tesh, Vernon L (2012) Activation of cell stress response pathways by Shiga toxins. Cell Microbiol 14:1-9
Lentz, Erin K; Leyva-Illades, Dinorah; Lee, Moo-Seung et al. (2011) Differential response of the human renal proximal tubular epithelial cell line HK-2 to Shiga toxin types 1 and 2. Infect Immun 79:3527-40
Lee, Moo-Seung; Cherla, Rama P; Jenson, Matthew H et al. (2011) Shiga toxins induce autophagy leading to differential signalling pathways in toxin-sensitive and toxin-resistant human cells. Cell Microbiol 13:1479-96
Lee, Moo-Seung; Cherla, Rama P; Lentz, Erin K et al. (2010) Signaling through C/EBP homologous protein and death receptor 5 and calpain activation differentially regulate THP-1 cell maturation-dependent apoptosis induced by Shiga toxin type 1. Infect Immun 78:3378-91
Lentz, Erin K; Cherla, Rama P; Jaspers, Valery et al. (2010) Role of tumor necrosis factor alpha in disease using a mouse model of Shiga toxin-mediated renal damage. Infect Immun 78:3689-99
Lee, Moo-Seung; Cherla, Rama P; Tesh, Vernon L (2010) Shiga toxins: intracellular trafficking to the ER leading to activation of host cell stress responses. Toxins (Basel) 2:1515-35
Leyva-Illades, Dinorah; Cherla, Rama P; Galindo, Cristi L et al. (2010) Global transcriptional response of macrophage-like THP-1 cells to Shiga toxin type 1. Infect Immun 78:2454-65
Tesh, Vernon L (2010) Induction of apoptosis by Shiga toxins. Future Microbiol 5:431-53

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