Adhesion and Signalling in CD4 + T Helper Cells

O'Rourke, Anne M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 2R01AI034684-04A1
• Application #: 2069831
• Study Section: Experimental Immunology Study Section (EI)
• Project Start: 1993-02-01
• Project End: 1999-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: Scripps Research Institute
• City: La Jolla
• State: CA
• Country: United States
• Zip Code: 92037

Publications

O'Rourke, A M; Shao, H; Kaye, J (1998) A role for p21ras/MAP kinase in TCR-mediated activation of LFA-1. J Immunol 161:5800-3

O'Rourke, A M; Escuro, G; Feeney, A J (1998) Cloning and sequencing of cDNA encoding mouse cytohesin-1. Immunogenetics 48:354-5

O'Rourke, A M; Webb, S R (1997) Cross talk between T and B cells generates B antigen-presenting cells able to induce inositol phosphate production in T cells responding to Mls(a) superantigens. Eur J Immunol 27:3253-8

Brunmark, A; O'Rourke, A M (1997) Augmentation of mature CD4+ T cell responses to isolated antigenic class II proteins by fibronectin and intercellular adhesion molecule-1. J Immunol 159:1676-85

O'Rourke, A M; Lasam, M C (1995) Murine CD4+ T cells undergo TCR-activated adhesion to extracellular matrix proteins but not to nonantigenic MHC class II proteins. J Immunol 155:3839-46