Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034704-03
Application #
2003983
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1998-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Locher, Christopher P; Witt, Stephanie A; Kassel, Rachel et al. (2005) Differential effects of R5 and X4 human immunodeficiency virus type 1 infection on CD4+ cell proliferation and activation. J Gen Virol 86:1171-9
Locher, Christopher P; Witt, Stephanie A; Ashlock, Brittany M et al. (2004) Human immunodeficiency virus type 2 DNA vaccine provides partial protection from acute baboon infection. Vaccine 22:2261-72
Locher, Christopher P; Witt, Stephanie A; Ashlock, Brittany M et al. (2004) Evaluation of genetic immunization adjuvants to improve the effectiveness of a human immunodeficiency virus type 2 (HIV-2) envelope DNA vaccine. DNA Cell Biol 23:107-10
Locher, Christopher P; Fujimura, Sue; Murthy, Krishna K et al. (2003) Expression patterns of phenotypic markers on lymphocytes from human immunodeficiency virus type 2-infected baboons. AIDS Res Hum Retroviruses 19:31-40
Locher, Christopher P; Putnam, David; Langer, Robert et al. (2003) Enhancement of a human immunodeficiency virus env DNA vaccine using a novel polycationic nanoparticle formulation. Immunol Lett 90:67-70
Locher, Christopher P; Witt, Stephanie A; Herndier, Brian G et al. (2003) Increased virus replication and virulence after serial passage of human immunodeficiency virus type 2 in baboons. J Virol 77:77-83
Locher, Christopher P; Witt, Stephanie A; Ashlock, Brittany M et al. (2002) Enhancement of antibody responses to an HIV-2 DNA envelope vaccine using an expression vector containing a constitutive transport element. DNA Cell Biol 21:581-6
Locher, C P; Sykes, K F; Blackbourn, D J et al. (2002) Immune responses in baboons vaccinated with HIV-2 genetic expression libraries. J Med Primatol 31:323-9
Locher, C P; Witt, S A; Herndier, B G et al. (2001) Baboons as an animal model for human immunodeficiency virus pathogenesis and vaccine development. Immunol Rev 183:127-40
Locher, C P; Blackbourn, D J; Levy, J A (1999) Suppression of human immunodeficiency virus type 1 replication by a soluble factor produced by CD8+ lymphocytes from HIV-2-infected baboons. Immunol Lett 66:151-7

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