Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034749-03
Application #
2069903
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1993-12-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Djekic, Uros V; Morrow, Casey D (2007) Analysis of the replication of HIV-1 forced to use tRNAMet(i) supports a link between primer selection, translation and encapsidation. Retrovirology 4:10
Yu, Wanfeng; McCulley, Anna; Morrow, Casey D (2007) Mutations in the TPsiC loop of E. coli tRNALys,3 have varied effects on in trans complementation of HIV-1 replication. Virol J 4:5
Palmer, Matthew T; Kirkman, Richard; Kosloff, Barry R et al. (2007) tRNA isoacceptor preference prior to retrovirus Gag-Pol junction links primer selection and viral translation. J Virol 81:4397-404
Ni, Na; Xu, Wenqin; Morrow, Casey D (2007) Importance of A-loop complementarity with tRNAHis anticodon for continued selection of tRNAHis as the HIV reverse transcription primer. Virol J 4:4
McCulley, Anna; Morrow, Casey D (2006) Complementation of human immunodeficiency virus type 1 replication by intracellular selection of Escherichia coli formula supplied in trans. J Virol 80:9641-50
Xu, Wenqin; Morrow, Casey D (2006) The G490E mutation in reverse transcriptase does not impact tRNA primer selection by HIV-1 with altered PBS and A-loop. Virology 352:380-9
Li, Meng; Eipers, Peter G; Ni, Na et al. (2006) HIV-1 designed to use different tRNAGln isoacceptors prefers to select tRNAThr for replication. Virol J 3:80
Moore-Rigdon, Kenda L; Kosloff, Barry R; Kirkman, Richard L et al. (2005) Preferences for the selection of unique tRNA primers revealed from analysis of HIV-1 replication in peripheral blood mononuclear cells. Retrovirology 2:21
Kelly, Nathan J; Morrow, Casey D (2005) Structural elements of the tRNA TPsiC loop critical for nucleocytoplasmic transport are important for human immunodeficiency virus type 1 primer selection. J Virol 79:6532-9
Palmer, Matthew T; McPherson, Sylvia; Morrow, Casey D (2005) Murine leukemia virus with a primer-binding site complementary to tRNALys,3 adapts to select new tRNAs for replication following extended in vitro culture. Virology 333:337-48

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