Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034875-03
Application #
2070092
Study Section
Immunobiology Study Section (IMB)
Project Start
1994-01-01
Project End
1997-06-30
Budget Start
1996-01-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
East Tennessee State University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Johnson City
State
TN
Country
United States
Zip Code
37614

  Publications

Mukhopadhyay, A; Suttles, J; Stout, R D et al. (2001) Genetic deletion of the tumor necrosis factor receptor p60 or p80 abrogates ligand-mediated activation of nuclear factor-kappa B and of mitogen-activated protein kinases in macrophages. J Biol Chem 276:31906-12
Hoellman, J R; Suttles, J; Stout, R D (2001) Panning T cells on vascular endothelial cell monolayers: a rapid method for enriching naive T cells. Immunobiology 203:769-77
Clemons-Miller, A R; Cox, G W; Suttles, J et al. (2000) LPS stimulation of TNF-receptor deficient macrophages: a differential role for TNF-alpha autocrine signaling in the induction of cytokine and nitric oxide production. Immunobiology 202:477-92
Suttles, J; Milhorn, D M; Miller, R W et al. (1999) CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory action. J Biol Chem 274:5835-42
Stout, R D; Suttles, J (1997) T cell signaling of macrophage function in inflammatory disease. Front Biosci 2:d197-206
Poe, J C; Wagner Jr, D H; Miller, R W et al. (1997) IL-4 and IL-10 modulation of CD40-mediated signaling of monocyte IL-1beta synthesis and rescue from apoptosis. J Immunol 159:846-52
Krishnaswamy, G; Lakshman, T; Miller, A R et al. (1997) Multifunctional cytokine expression by human mast cells: regulation by T cell membrane contact and glucocorticoids. J Interferon Cytokine Res 17:167-76
Suttles, J; Evans, M; Miller, R W et al. (1996) T cell rescue of monocytes from apoptosis: role of the CD40-CD40L interaction and requirement for CD40-mediated induction of protein tyrosine kinase activity. J Leukoc Biol 60:651-7
Miller, A R; Suttles, J; Stout, R D (1996) Cytokine priming reduces dependence on TNF-R2 for TNF-alpha-mediated induction of macrophage nitric oxide generation. J Interferon Cytokine Res 16:1055-63
Stout, R D; Suttles, J; Xu, J et al. (1996) Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice. J Immunol 156:8-11

Showing the most recent 10 out of 13 publications