Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI035275-04
Application #
2070842
Study Section
Special Emphasis Panel (SRC (36))
Project Start
1993-09-30
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Horwitz, Lawrence D; Horwitz, Marcus A (2014) The exochelins of pathogenic mycobacteria: unique, highly potent, lipid- and water-soluble hexadentate iron chelators with multiple potential therapeutic uses. Antioxid Redox Signal 21:2246-61
Clemens, Daniel L; Lee, Bai-Yu; Horwitz, Marcus A (2002) The Mycobacterium tuberculosis phagosome in human macrophages is isolated from the host cell cytoplasm. Infect Immun 70:5800-7
Land, K M; Clemens, D L; Johnson, P J (2001) Loss of multiple hydrogenosomal proteins associated with organelle metabolism and high-level drug resistance in trichomonads. Exp Parasitol 97:102-10
Pahl, P M; Horwitz, M A; Horwitz, K B et al. (2001) Desferri-exochelin induces death by apoptosis in human breast cancer cells but does not kill normal breast cells. Breast Cancer Res Treat 69:69-79
Byrd, T F; Horwitz, M A (2000) Aberrantly low transferrin receptor expression on human monocytes is associated with nonpermissiveness for Legionella pneumophila growth. J Infect Dis 181:1394-400
Clemens, D L; Johnson, P J (2000) Failure to detect DNA in hydrogenosomes of Trichomonas vaginalis by nick translation and immunomicroscopy. Mol Biochem Parasitol 106:307-13
Clemens, D L; Lee, B Y; Horwitz, M A (2000) Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate. Infect Immun 68:2671-84
Clemens, D L; Lee, B Y; Horwitz, M A (2000) Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7. Infect Immun 68:5154-66
Gobin, J; Wong, D K; Gibson, B W et al. (1999) Characterization of exochelins of the Mycobacterium bovis type strain and BCG substrains. Infect Immun 67:2035-9
Calder, K M; Horwitz, M A (1998) Identification of iron-regulated proteins of Mycobacterium tuberculosis and cloning of tandem genes encoding a low iron-induced protein and a metal transporting ATPase with similarities to two-component metal transport systems. Microb Pathog 24:133-43

Showing the most recent 10 out of 19 publications