Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI035678-04
Application #
2672309
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1995-04-01
Project End
2000-03-31
Budget Start
1997-10-01
Budget End
1998-03-31
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Duke University
Department
Pathology
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Abraham, Soman N; Miao, Yuxuan (2015) The nature of immune responses to urinary tract infections. Nat Rev Immunol 15:655-63
Miao, Yuxuan; Li, Guojie; Zhang, Xiaoli et al. (2015) A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion. Cell 161:1306-19
St John, Ashley L; Ang, W X Gladys; Huang, Min-Nung et al. (2014) S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection. Immunity 41:440-450
St John, Ashley L; Chan, Cheryl Y; Staats, Herman F et al. (2012) Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes. Nat Mater 11:250-7
Abraham, Soman N; St John, Ashley L (2010) Mast cell-orchestrated immunity to pathogens. Nat Rev Immunol 10:440-52
St John, Ashley L; Abraham, Soman N (2009) Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines. Nat Med 15:1259-65
Bishop, Brian L; Duncan, Mathew J; Song, Jeongmin et al. (2007) Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells. Nat Med 13:625-30
Shin, Jeoung-Sook; Shelburne, Christopher P; Jin, Cong et al. (2006) Harboring of particulate allergens within secretory compartments by mast cells following IgE/FcepsilonRI-lipid raft-mediated phagocytosis. J Immunol 177:5791-800
Feger, Frederic; Varadaradjalou, Sonia; Gao, Zhimin et al. (2002) The role of mast cells in host defense and their subversion by bacterial pathogens. Trends Immunol 23:151-8
Shin, J S; Abraham, S N (2001) Caveolae as portals of entry for microbes. Microbes Infect 3:755-61

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