Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI035934-03
Application #
2071914
Study Section
Special Emphasis Panel (SRC (25))
Project Start
1994-05-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Depaolo, R William; Lathan, Rashida; Rollins, Barrett J et al. (2005) The chemokine CCL2 is required for control of murine gastric Salmonella enterica infection. Infect Immun 73:6514-22
DePaolo, R William; Lathan, Rashida; Karpus, William J (2004) CCR5 regulates high dose oral tolerance by modulating CC chemokine ligand 2 levels in the GALT. J Immunol 173:314-20
Dogan, Rukiye-Nazan E; Karpus, William J (2004) Chemokines and chemokine receptors in autoimmune encephalomyelitis as a model for central nervous system inflammatory disease regulation. Front Biosci 9:1500-5
DePaolo, R William; Rollins, Barrett J; Kuziel, William et al. (2003) CC chemokine ligand 2 and its receptor regulate mucosal production of IL-12 and TGF-beta in high dose oral tolerance. J Immunol 171:3560-7
Karpus, W J (2001) Chemokines and central nervous system disorders. J Neurovirol 7:493-500
Kennedy, K J; Karpus, W J (1999) Role of chemokines in the regulation of Th1/Th2 and autoimmune encephalomyelitis. J Clin Immunol 19:273-9
Hoffman, L M; Fife, B T; Begolka, W S et al. (1999) Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease. J Neurovirol 5:635-42
Hoffman, L M; Karpus, W J (1998) Chemokine regulation of CNS T-cell infiltration in experimental autoimmune encephalomyelitis. Res Immunol 149:790-4;discussion 846-7, 855-60
Karpus, W J; Kennedy, K J; Kunkel, S L et al. (1998) Monocyte chemotactic protein 1 regulates oral tolerance induction by inhibition of T helper cell 1-related cytokines. J Exp Med 187:733-41
Karpus, W J; Ransohoff, R M (1998) Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis. J Immunol 161:2667-71

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