Immunopathic Myositis Induced by Persistent Virus

Messner, Ronald P.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI036223-04
• Application #: 2072373
• Study Section: Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
• Project Start: 1993-09-30
• Project End: 1997-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Minnesota Twin Cities
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 168559177
• City: Minneapolis
• State: MN
• Country: United States
• Zip Code: 55455

Publications

Tam, Patricia E; Weber-Sanders, Melissa L; Messner, Ronald P (2003) Multiple viral determinants mediate myopathogenicity in coxsackievirus B1-induced chronic inflammatory myopathy. J Virol 77:11849-54

Tam, Patricia E; Fontana, Donna R; Messner, Ronald P (2003) Coxsackievirus B1-induced chronic inflammatory myopathy: differences in induction of autoantibodies to muscle and nuclear antigens by cloned myopathic and amyopathic viruses. J Lab Clin Med 142:196-204

Tam, P E; Messner, R P (1999) Molecular mechanisms of coxsackievirus persistence in chronic inflammatory myopathy: viral RNA persists through formation of a double-stranded complex without associated genomic mutations or evolution. J Virol 73:10113-21

Tam, P E; Messner, R P (1997) Coxsackievirus-induced chronic inflammatory myopathy: virus variants distinguish between acute cytopathic effects and pathogenesis of chronic disease. Virology 233:199-209

Tam, P E; Messner, R P (1996) Genetic determinants of susceptibility to coxsackievirus B1-induced chronic inflammatory myopathy: effects of host background and major histocompatibility complex genes. J Lab Clin Med 128:279-89