Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI036519-03
Application #
2072847
Study Section
Special Emphasis Panel (SRC (35))
Project Start
1994-08-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tulane University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
New Orleans
State
LA
Country
United States
Zip Code
70118
Tacket, Carol O (2007) Plant-based vaccines against diarrheal diseases. Trans Am Clin Climatol Assoc 118:79-87
Estes, M K; Ball, J M; Guerrero, R A et al. (2000) Norwalk virus vaccines: challenges and progress. J Infect Dis 181 Suppl 2:S367-73
Freytag, L C; Clements, J D (1999) Bacterial toxins as mucosal adjuvants. Curr Top Microbiol Immunol 236:215-36
Tacket, C O; Mason, H S; Losonsky, G et al. (1998) Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. Nat Med 4:607-9
Chong, C; Friberg, M; Clements, J D (1998) LT(R192G), a non-toxic mutant of the heat-labile enterotoxin of Escherichia coli, elicits enhanced humoral and cellular immune responses associated with protection against lethal oral challenge with Salmonella spp. Vaccine 16:732-40
Ball, J M; Hardy, M E; Atmar, R L et al. (1998) Oral immunization with recombinant Norwalk virus-like particles induces a systemic and mucosal immune response in mice. J Virol 72:1345-53
Mason, H S; Haq, T A; Clements, J D et al. (1998) Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene. Vaccine 16:1336-43
Estes, M K; Ball, J M; Crawford, S E et al. (1997) Virus-like particle vaccines for mucosal immunization. Adv Exp Med Biol 412:387-95
Guidry, J J; Cardenas, L; Cheng, E et al. (1997) Role of receptor binding in toxicity, immunogenicity, and adjuvanticity of Escherichia coli heat-labile enterotoxin. Infect Immun 65:4943-50
Ball, J M; Estes, M K; Hardy, M E et al. (1996) Recombinant Norwalk virus-like particles as an oral vaccine. Arch Virol Suppl 12:243-9

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