Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI036936-01A2
Application #
2073475
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Baylor College of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Amini-Vaughan, Zhaleh J; Martinez-Moczygemba, Margarita; Huston, David P (2012) Therapeutic strategies for harnessing human eosinophils in allergic inflammation, hypereosinophilic disorders, and cancer. Curr Allergy Asthma Rep 12:402-12
Martinez-Moczygemba, Margarita; Huston, David P (2010) Immune dysregulation in the pathogenesis of pulmonary alveolar proteinosis. Curr Allergy Asthma Rep 10:320-5
Martinez-Moczygemba, Margarita; Doan, Minh L; Elidemir, Okan et al. (2008) Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1. J Exp Med 205:2711-6
Martinez-Moczygemba, Margarita; Huston, David P; Lei, Jonathan T (2007) JAK kinases control IL-5 receptor ubiquitination, degradation, and internalization. J Leukoc Biol 81:1137-48
Ng, Bernard; Yang, Fan; Huston, David P et al. (2004) Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes. J Allergy Clin Immunol 114:1463-70
Martinez-Moczygemba, Margarita; Huston, David P (2003) Biology of common beta receptor-signaling cytokines: IL-3, IL-5, and GM-CSF. J Allergy Clin Immunol 112:653-65; quiz 666
Martinez-Moczygemba, M; Huston, D P (2001) Proteasomal regulation of betac signaling reveals a novel mechanism for cytokine receptor heterotypic desensitization. J Clin Invest 108:1797-806
Huston, D P; Huston, M M; Dickason, R R et al. (2000) Interleukin-5, a therapeutic target in allergic inflammation. Trans Am Clin Climatol Assoc 111:46-59; discussion 59-60
Bressler, R B; Lesko, J; Jones, M L et al. (1997) Production of IL-5 and granulocyte-macrophage colony-stimulating factor by naive human mast cells activated by high-affinity IgE receptor ligation. J Allergy Clin Immunol 99:508-14
Dickason, R R; English, J D; Huston, D P (1996) Engineering of a functional interleukin-5 monomer: a paradigm for redesigning helical bundle cytokines with therapeutic potential in allergy and asthma. J Mol Med 74:535-46