Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI036997-02
Application #
2073571
Study Section
Immunobiology Study Section (IMB)
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Corn, Radiah A; Aronica, Mark A; Zhang, Fuping et al. (2003) T cell-intrinsic requirement for NF-kappa B induction in postdifferentiation IFN-gamma production and clonal expansion in a Th1 response. J Immunol 171:1816-24
Mora, A L; Corn, R A; Stanic, A K et al. (2003) Antiapoptotic function of NF-kappaB in T lymphocytes is influenced by their differentiation status: roles of Fas, c-FLIP, and Bcl-xL. Cell Death Differ 10:1032-44
Mora, A L; Stanley, S; Armistead, W et al. (2001) Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel. J Immunol 167:5628-35
Boothby, M; Mora, A L; Stephenson, L M (2001) Lymphokine-dependent proliferation of T-lymphoid cells: regulated responsiveness and role in vivo. Crit Rev Immunol 21:487-522
Mora, A; Youn, J; Keegan, A et al. (2001) NF-kappa B/Rel participation in the lymphokine-dependent proliferation of T lymphoid cells. J Immunol 166:2218-27
Aronica, M A; Goenka, S; Boothby, M (2000) IL-4-dependent induction of BCL-2 and BCL-X(L)IN activated T lymphocytes through a STAT6- and pi 3-kinase-independent pathway. Cytokine 12:578-87
Aune, T M; Mora, A L; Kim, S et al. (1999) Costimulation reverses the defect in IL-2 but not effector cytokine production by T cells with impaired IkappaBalpha degradation. J Immunol 162:5805-12
Aronica, M A; Mora, A L; Mitchell, D B et al. (1999) Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo. J Immunol 163:5116-24
Seetharaman, R; Mora, A L; Nabozny, G et al. (1999) Essential role of T cell NF-kappa B activation in collagen-induced arthritis. J Immunol 163:1577-83
Mora, A L; Chen, D; Boothby, M et al. (1999) Lineage-specific differences among CD8+ T cells in their dependence of NF-kappa B/Rel signaling. Eur J Immunol 29:2968-80

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