Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037186-03
Application #
2073832
Study Section
Special Emphasis Panel (SRC (58))
Project Start
1994-09-30
Project End
1998-03-31
Budget Start
1996-09-01
Budget End
1998-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Leifert, Jens A; Rodriguez-Carreno, Maria P; Rodriguez, Fernando et al. (2004) Targeting plasmid-encoded proteins to the antigen presentation pathways. Immunol Rev 199:40-53
Benning, Nicola; Hassett, Daniel E (2004) Vaccinia virus infection during murine pregnancy: a new pathogenesis model for vaccinia fetalis. J Virol 78:3133-9
Leifert, J A; Holler, P D; Harkins, S et al. (2003) The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes. Gene Ther 10:2067-73
Leifert, Jens A; Whitton, J Lindsay (2003) ""Translocatory proteins"" and ""protein transduction domains"": a critical analysis of their biological effects and the underlying mechanisms. Mol Ther 8:13-20
Leifert, J A; Harkins, S; Whitton, J L (2002) Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity. Gene Ther 9:1422-8
Zhang, Jie; Silvestri, Nicole; Whitton, J Lindsay et al. (2002) Neonates mount robust and protective adult-like CD8(+)-T-cell responses to DNA vaccines. J Virol 76:11911-9
Whitton, J L (2002) Designing arenaviral vaccines. Curr Top Microbiol Immunol 263:221-38
Theil, D J; Tsunoda, I; Rodriguez, F et al. (2001) Viruses can silently prime for and trigger central nervous system autoimmune disease. J Neurovirol 7:220-7
Whitton, J L; Fujinami, R S (2001) DNA immunization and central nervous system viral infection. Adv Virus Res 56:243-73
Leifert, J A; Lindencrona, J A; Charo, J et al. (2001) Enhancing T cell activation and antiviral protection by introducing the HIV-1 protein transduction domain into a DNA vaccine. Hum Gene Ther 12:1881-92

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