Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037305-03
Application #
2074003
Study Section
Special Emphasis Panel (SRC (58))
Project Start
1994-09-30
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
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Raz, E; Spiegelberg, H L (1999) Deviation of the allergic IgE to an IgG response by gene immunotherapy. Int Rev Immunol 18:271-89
Tighe, H; Corr, M; Roman, M et al. (1998) Gene vaccination: plasmid DNA is more than just a blueprint. Immunol Today 19:89-97
Roman, M; Spiegelberg, H L; Broide, D et al. (1997) Gene immunization for allergic disorders. Springer Semin Immunopathol 19:223-32
Lee, D J; Tighe, H; Corr, M et al. (1997) Inhibition of IgE antibody formation by plasmid DNA immunization is mediated by both CD4+ and CD8+ T cells. Int Arch Allergy Immunol 113:227-30
Roman, M; Martin-Orozco, E; Goodman, J S et al. (1997) Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nat Med 3:849-54
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Raz, E (1997) Introduction: gene vaccination, current concepts and future directions. Springer Semin Immunopathol 19:131-7
Raz, E; Tighe, H; Sato, Y et al. (1996) Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci U S A 93:5141-5
Sato, Y; Roman, M; Tighe, H et al. (1996) Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 273:352-4