Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI037475-01A1
Application #
2074224
Study Section
Special Emphasis Panel (ZRG5-ARRG (01))
Project Start
1995-05-01
Project End
1995-10-13
Budget Start
1995-05-01
Budget End
1995-10-13
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198
Brandano, Laura; Stevenson, Mario (2012) A highly conserved residue in the C-terminal helix of HIV-1 matrix is required for envelope incorporation into virus particles. J Virol 86:2347-59
Kaushik, Rajnish; Zhu, Xiaonan; Stranska, Ruzena et al. (2009) A cellular restriction dictates the permissivity of nondividing monocytes/macrophages to lentivirus and gammaretrovirus infection. Cell Host Microbe 6:68-80
Sharova, Natalia; Wu, Yuanfei; Zhu, Xiaonan et al. (2008) Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction. PLoS Pathog 4:e1000057
Zielske, Steven P; Stevenson, Mario (2006) Modest but reproducible inhibition of human immunodeficiency virus type 1 infection in macrophages following LEDGFp75 silencing. J Virol 80:7275-80
Zielske, Steven P; Stevenson, Mario (2005) Importin 7 may be dispensable for human immunodeficiency virus type 1 and simian immunodeficiency virus infection of primary macrophages. J Virol 79:11541-6
Triques, Karine; Stevenson, Mario (2004) Characterization of restrictions to human immunodeficiency virus type 1 infection of monocytes. J Virol 78:5523-7
Chiu, Ya-Lin; Cao, Hong; Jacque, Jean-Marc et al. (2004) Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1). J Virol 78:2517-29
Somasundaran, Mohan; Sharkey, Mark; Brichacek, Beda et al. (2002) Evidence for a cytopathogenicity determinant in HIV-1 Vpr. Proc Natl Acad Sci U S A 99:9503-8
Sleigh, R; Sharkey, M; Newman, M A et al. (1998) Differential association of uracil DNA glycosylase with SIVSM Vpr and Vpx proteins. Virology 245:338-43
Hirsch, V M; Sharkey, M E; Brown, C R et al. (1998) Vpx is required for dissemination and pathogenesis of SIV(SM) PBj: evidence of macrophage-dependent viral amplification. Nat Med 4:1401-8

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