Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI038348-01A1
Application #
2075366
Study Section
Special Emphasis Panel (ZRG2-ALY (01))
Project Start
1996-06-15
Project End
2001-05-31
Budget Start
1996-06-15
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
009214214
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Kashiwakura, Jun-ichi; Xiao, Wenbin; Kitaura, Jiro et al. (2008) Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype. J Leukoc Biol 84:357-67
Hong, Hong; Kitaura, Jiro; Xiao, Wenbin et al. (2007) The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn. Blood 110:2511-9
Kitaura, Jiro; Kawakami, Yuko; Maeda-Yamamoto, Mari et al. (2007) Dysregulation of Src family kinases in mast cells from epilepsy-resistant ASK versus epilepsy-prone EL mice. J Immunol 178:455-62
Kawakami, Yuko; Inagaki, Naoki; Salek-Ardakani, Shahram et al. (2006) Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3. Proc Natl Acad Sci U S A 103:153-8
Okayama, Yoshimichi; Kawakami, Toshiaki (2006) Development, migration, and survival of mast cells. Immunol Res 34:97-115
Moreno-Garcia, Miguel E; Lopez-Bojorques, Lucia N; Zentella, Alejandro et al. (2005) CD38 signaling regulates B lymphocyte activation via a phospholipase C (PLC)-gamma 2-independent, protein kinase C, phosphatidylcholine-PLC, and phospholipase D-dependent signaling cascade. J Immunol 174:2687-95
Kitaura, Jiro; Kinoshita, Tatsuya; Matsumoto, Masaaki et al. (2005) IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion. Blood 105:3222-9
Xiao, Wenbin; Nishimoto, Hajime; Hong, Hong et al. (2005) Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI. J Immunol 175:6885-92
Kitaura, Jiro; Eto, Koji; Kinoshita, Tatsuya et al. (2005) Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases. J Immunol 174:4495-504
Nishimoto, Hajime; Lee, Seung-Woo; Hong, Hong et al. (2005) Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor. Blood 106:4241-8

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