Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI038559-02
Application #
2004347
Study Section
Special Emphasis Panel (SRC (55))
Project Start
1995-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Kaur, A; Alexander, L; Staprans, S I et al. (2001) Emergence of cytotoxic T lymphocyte escape mutations in nonpathogenic simian immunodeficiency virus infection. Eur J Immunol 31:3207-17
Vajdy, M; Veazey, R S; Knight, H K et al. (2000) Differential effects of simian immunodeficiency virus infection on immune inductive and effector sites in the rectal mucosa of rhesus macaques. Am J Pathol 157:485-95
Kaur, A; Yang, J; Hempel, D et al. (2000) Identification of multiple simian immunodeficiency virus (SIV)-specific CTL epitopes in sooty mangabeys with natural and experimentally acquired SIV infection. J Immunol 164:934-43
Kaur, A; Hale, C L; Ramanujan, S et al. (2000) Differential dynamics of CD4(+) and CD8(+) T-lymphocyte proliferation and activation in acute simian immunodeficiency virus infection. J Virol 74:8413-24
Alexander, L; Weiskopf, E; Greenough, T C et al. (2000) Unusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection. J Virol 74:4361-76
Alexander, L; Du, Z; Howe, A Y et al. (1999) Induction of AIDS in rhesus monkeys by a recombinant simian immunodeficiency virus expressing nef of human immunodeficiency virus type 1. J Virol 73:5814-25
Kaur, A; Grant, R M; Means, R E et al. (1998) Diverse host responses and outcomes following simian immunodeficiency virus SIVmac239 infection in sooty mangabeys and rhesus macaques. J Virol 72:9597-611
Howe, A Y; Jung, J U; Desrosiers, R C (1998) Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2. J Virol 72:9827-34
Veazey, R S; DeMaria, M; Chalifoux, L V et al. (1998) Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 280:427-31
Wykrzykowska, J J; Rosenzweig, M; Veazey, R S et al. (1998) Early regeneration of thymic progenitors in rhesus macaques infected with simian immunodeficiency virus. J Exp Med 187:1767-78

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