Rude, M A; Khosla, C (2006) Production of ansamycin polyketide precursors in Escherichia coli. J Antibiot (Tokyo) 59:464-70
|
Hartung, Ingo V; Rude, Mathew A; Schnarr, Nathan A et al. (2005) Stereochemical assignment of intermediates in the rifamycin biosynthetic pathway by precursor-directed biosynthesis. J Am Chem Soc 127:11202-3
|
Admiraal, Suzanne J; Khosla, Chaitan; Walsh, Christopher T (2002) The loading and initial elongation modules of rifamycin synthetase collaborate to produce mixed aryl ketide products. Biochemistry 41:5313-24
|
Admiraal, S J; Walsh, C T; Khosla, C (2001) The loading module of rifamycin synthetase is an adenylation-thiolation didomain with substrate tolerance for substituted benzoates. Biochemistry 40:6116-23
|
Doi-Katayama, Y; Yoon, Y J; Choi, C Y et al. (2000) Thioesterases and the premature termination of polyketide chain elongation in rifamycin B biosynthesis by Amycolatopsis mediterranei S699. J Antibiot (Tokyo) 53:484-95
|
Yu, T W; Shen, Y; Doi-Katayama, Y et al. (1999) Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively. Proc Natl Acad Sci U S A 96:9051-6
|
Hu, Z; Hunziker, D; Hutchinson, C R et al. (1999) A host-vector system for analysis and manipulation of rifamycin polyketide biosynthesis in Amycolatopsis mediterranei. Microbiology 145 ( Pt 9):2335-41
|
August, P R; Tang, L; Yoon, Y J et al. (1998) Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699. Chem Biol 5:69-79
|