Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI039026-01A1
Application #
2076136
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1996-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Surgery
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Stepkowski, Stanislaw M; Kao, Judy; Wang, Mou-Er et al. (2005) The Mannich base NC1153 promotes long-term allograft survival and spares the recipient from multiple toxicities. J Immunol 175:4236-46
Tian, L; Qu, X; Wang, M E et al. (2001) Selective inhibition of IL-2 mRNA blocks allograft rejection by limiting T cell clonal expansion. Transplant Proc 33:330
Qu, X; Kirken, R A; Tian, L et al. (2001) Selective inhibition of IL-2 gene expression by IL-2 antisense oligonucleotides blocks heart allograft rejection. Transplantation 72:915-23
Behbod, F; Erwin-Cohen, R A; Wang, M E et al. (2001) Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts. J Immunol 166:3724-32
Stepkowski, S M; Chen, W; Bennett, C F et al. (2001) Phosphorothioate/methoxyethyl-modified ICAM-1 antisense oligonucleotides improves prevention of ischemic/reperfusion injury. Transplant Proc 33:3705-6
Chen, W; Bennett, C F; Condon, T P et al. (2001) Methoxyethyl modification of phosphorothioate ICAM-1 antisense oligonucleotides improves prevention of ischemic/reperfusion injury. Transplant Proc 33:854
Stepkowski, S M; Chen, W; Geary, R et al. (2001) Development of an oral formulation for ICAM-1 antisense oligonucleotides. Transplant Proc 33:387
Katz, S M; Bennett, F; Stecker, K et al. (2000) ICAM-1 antisense oligodeoxynucleotide improves islet allograft survival and function. Cell Transplant 9:817-28
Stepkowski, S M; Qu, X; Wang, M E et al. (2000) Inhibition of C-raf expression by antisense oligonucleotides extends heart allograft survival in rats. Transplantation 70:656-61
Stepkowski, S M (2000) Development of antisense oligodeoxynucleotides for transplantation. Curr Opin Mol Ther 2:304-17

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