Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI039098-01
Application #
2076206
Study Section
Immunobiology Study Section (IMB)
Project Start
1996-03-01
Project End
2000-02-29
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Sasada, Tetsuro; Touma, Maki; Chang, Hsiu-Ching et al. (2002) Involvement of the TCR Cbeta FG loop in thymic selection and T cell function. J Exp Med 195:1419-31
Witte, T; Spoerl, R; Chang, H C (1999) The CD8beta ectodomain contributes to the augmented coreceptor function of CD8alphabeta heterodimers relative to CD8alphaalpha homodimers. Cell Immunol 191:90-6
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Ghendler, Y; Smolyar, A; Chang, H C et al. (1998) One of the CD3epsilon subunits within a T cell receptor complex lies in close proximity to the Cbeta FG loop. J Exp Med 187:1529-36
Ghendler, Y; Hussey, R E; Witte, T et al. (1997) Double-positive T cell receptor(high) thymocytes are resistant to peptide/major histocompatibility complex ligand-induced negative selection. Eur J Immunol 27:2279-89
Khandekar, S S; Brauer, P P; Naylor, J W et al. (1997) Affinity and kinetics of the interactions between an alphabeta T-cell receptor and its superantigen and class II-MHC/peptide ligands. Mol Immunol 34:493-503
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