Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI039420-01A1
Application #
2076498
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Aaron Diamond AIDS Research Center
Department
Type
DUNS #
786658872
City
New York
State
NY
Country
United States
Zip Code
10016
Xiang, Shi-Hua; Finzi, Andrés; Pacheco, Beatriz et al. (2010) A V3 loop-dependent gp120 element disrupted by CD4 binding stabilizes the human immunodeficiency virus envelope glycoprotein trimer. J Virol 84:3147-61
Yuan, Wen; Li, Xing; Kasterka, Marta et al. (2009) Oligomer-specific conformations of the human immunodeficiency virus (HIV-1) gp41 envelope glycoprotein ectodomain recognized by human monoclonal antibodies. AIDS Res Hum Retroviruses 25:319-28
Kassa, Aemro; Madani, Navid; Schön, Arne et al. (2009) Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain. J Virol 83:8364-78
Kassa, Aemro; Finzi, Andres; Pancera, Marie et al. (2009) Identification of a human immunodeficiency virus type 1 envelope glycoprotein variant resistant to cold inactivation. J Virol 83:4476-88
Yang, Xinzhen; Lipchina, Inna; Lifton, Michelle et al. (2007) Antibody binding in proximity to the receptor/glycoprotein complex leads to a basal level of virus neutralization. J Virol 81:8809-13
Yang, Xinzhen; Lipchina, Inna; Cocklin, Simon et al. (2006) Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization. J Virol 80:11404-8
Yuan, Wen; Bazick, Jessica; Sodroski, Joseph (2006) Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker. J Virol 80:6725-37
Xiang, Shi-Hua; Farzan, Michael; Si, Zhihai et al. (2005) Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody. J Virol 79:6068-77
Mische, Claudia C; Yuan, Wen; Strack, Bettina et al. (2005) An alternative conformation of the gp41 heptad repeat 1 region coiled coil exists in the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor. Virology 338:133-43
Ren, Xinping; Sodroski, Joseph; Yang, Xinzhen (2005) An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins. J Virol 79:5616-24

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