Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI039466-01
Application #
2076547
Study Section
Virology Study Section (VR)
Project Start
1996-09-30
Project End
2001-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Patterson, J B; Manchester, M; Oldstone, M B (2001) Disease model: dissecting the pathogenesis of the measles virus. Trends Mol Med 7:85-8
Manchester, M; Eto, D S; Valsamakis, A et al. (2000) Clinical isolates of measles virus use CD46 as a cellular receptor. J Virol 74:3967-74
Naniche, D (2000) Generalized immunosuppression: individual viruses, intertwined targets. Virology 275:227-32
Naniche, D; Yeh, A; Eto, D et al. (2000) Evasion of host defenses by measles virus: wild-type measles virus infection interferes with induction of Alpha/Beta interferon production. J Virol 74:7478-84
Tishon, A; LaFace, D M; Lewicki, H et al. (2000) Transgenic mice expressing human HLA and CD8 molecules generate HLA-restricted measles virus cytotoxic T lymphocytes of the same specificity as humans with natural measles virus infection. Virology 275:286-93
Patterson, J B; Thomas, D; Lewicki, H et al. (2000) V and C proteins of measles virus function as virulence factors in vivo. Virology 267:80-9
Naniche, D; Oldstone, M B (2000) Generalized immunosuppression: how viruses undermine the immune response. Cell Mol Life Sci 57:1399-407
Patterson, J B; Scheiflinger, F; Manchester, M et al. (1999) Structural and functional studies of the measles virus hemagglutinin: identification of a novel site required for CD46 interaction. Virology 256:142-51
Naniche, D; Reed, S I; Oldstone, M B (1999) Cell cycle arrest during measles virus infection: a G0-like block leads to suppression of retinoblastoma protein expression. J Virol 73:1894-901
Rall, G F; Manchester, M; Daniels, L R et al. (1997) A transgenic mouse model for measles virus infection of the brain. Proc Natl Acad Sci U S A 94:4659-63

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