Regulation of Immunoglobulin Lambda

Storb, Ursula B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 1R01AI039535-01
• Application #: 2076598
• Study Section: Allergy and Immunology Study Section (ALY)
• Project Start: 1996-07-01
• Project End: 2001-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of Chicago
• Department: Genetics
• Type: Schools of Medicine
• DUNS #: 225410919
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60637

Publications

Volgina, Veronica V; Sun, Tianhe; Bozek, Grazyna et al. (2007) Scarcity of lambda 1 B cells in mice with a single point mutation in C lambda 1 is due to a low BCR signal caused by misfolded lambda 1 light chain. Mol Immunol 44:1417-28

Padjen, Kristoffer; Ratnam, Sarayu; Storb, Ursula (2005) DNA methylation precedes chromatin modifications under the influence of the strain-specific modifier Ssm1. Mol Cell Biol 25:4782-91

Sun, Tianhe; Clark, Marcus R; Storb, Ursula (2002) A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling. Immunity 16:245-55

Sun, T; Storb, U (2001) Insertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangement. J Exp Med 193:699-712

Satyaraj, E; Storb, U (1998) Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer. J Immunol 161:4795-802