Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI039544-01
Application #
2076607
Study Section
Virology Study Section (VR)
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wadsworth Center
Department
Type
DUNS #
110521739
City
Menands
State
NY
Country
United States
Zip Code
12204
Masters, Paul S; Kuo, Lili; Ye, Rong et al. (2006) Genetic and molecular biological analysis of protein-protein interactions in coronavirus assembly. Adv Exp Med Biol 581:163-73
Goebel, Scott J; Hsue, Bilan; Dombrowski, Todd F et al. (2004) Characterization of the RNA components of a putative molecular switch in the 3' untranslated region of the murine coronavirus genome. J Virol 78:669-82
Goebel, Scott J; Taylor, Jill; Masters, Paul S (2004) The 3' cis-acting genomic replication element of the severe acute respiratory syndrome coronavirus can function in the murine coronavirus genome. J Virol 78:7846-51
Ye, Rong; Montalto-Morrison, Cynthia; Masters, Paul S (2004) Genetic analysis of determinants for spike glycoprotein assembly into murine coronavirus virions: distinct roles for charge-rich and cysteine-rich regions of the endodomain. J Virol 78:9904-17
Trifilo, Matthew J; Montalto-Morrison, Cynthia; Stiles, Linda N et al. (2004) CXC chemokine ligand 10 controls viral infection in the central nervous system: evidence for a role in innate immune response through recruitment and activation of natural killer cells. J Virol 78:585-94
Kuo, Lili; Masters, Paul S (2003) The small envelope protein E is not essential for murine coronavirus replication. J Virol 77:4597-608
de Haan, Cornelis A M; de Wit, Marel; Kuo, Lili et al. (2003) The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain. Virology 312:395-406
Kuo, Lili; Masters, Paul S (2002) Genetic evidence for a structural interaction between the carboxy termini of the membrane and nucleocapsid proteins of mouse hepatitis virus. J Virol 76:4987-99
Shen, X; Masters, P S (2001) Evaluation of the role of heterogeneous nuclear ribonucleoprotein A1 as a host factor in murine coronavirus discontinuous transcription and genome replication. Proc Natl Acad Sci U S A 98:2717-22
Ontiveros, E; Kuo, L; Masters, P S et al. (2001) Inactivation of expression of gene 4 of mouse hepatitis virus strain JHM does not affect virulence in the murine CNS. Virology 289:230-8

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