Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI039576-07
Application #
6770172
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Korpela, Jukka K
Project Start
1997-05-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
7
Fiscal Year
2004
Total Cost
$385,600
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Sen, Jayita; Liu, Xueqiao; Roller, Richard et al. (2013) Herpes simplex virus US3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF6 ubiquitination. Virology 439:65-73
Duan, Jinyou; Kasper, Dennis L (2011) Oxidative depolymerization of polysaccharides by reactive oxygen/nitrogen species. Glycobiology 21:401-9
Murawski, Matthew R; McGinnes, Lori W; Finberg, Robert W et al. (2010) Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology. J Virol 84:1110-23
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van Lint, Allison L; Murawski, Matthew R; Goodbody, Rory E et al. (2010) Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling. J Virol 84:10802-11
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Dasgupta, Suryasarathi; Kasper, Dennis L (2010) Novel tools for modulating immune responses in the host-polysaccharides from the capsule of commensal bacteria. Adv Immunol 106:61-91
Velez, Christopher D; Lewis, Colleen J; Kasper, Dennis L et al. (2009) Type I Streptococcus pneumoniae carbohydrate utilizes a nitric oxide and MHC II-dependent pathway for antigen presentation. Immunology 127:73-82
Duan, Jinyou; Avci, Fikri Y; Kasper, Dennis L (2008) Microbial carbohydrate depolymerization by antigen-presenting cells: deamination prior to presentation by the MHCII pathway. Proc Natl Acad Sci U S A 105:5183-8
Mazmanian, Sarkis K; Round, June L; Kasper, Dennis L (2008) A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 453:620-5

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