Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI039793-02
Application #
2076801
Study Section
Special Emphasis Panel (SRC (23))
Project Start
1995-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Surgery
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Goldstein, D R; Thomas, J M; Kirklin, J K et al. (2001) An essential role for natural killer cells in augmentation of allograft survival mediated by donor spleen cells. Transplantation 72:954-6
Goldstein, D R; Thomas, J M; Kirklin, J K et al. (2001) Indefinite allograft survival mediated by donor bone marrow is dependent on the presence of a functional CD95 (Fas) gene in recipients. J Heart Lung Transplant 20:1132-5
Goldstein, D R; Chang, T; Sweeney, S D et al. (2000) Enhanced allograft survival induced by posttransplant donor spleen cell infusion occurs via a mechanism that is distinct from the mechanism of enhancement by donor bone marrow. Transplantation 69:1020-2
Contreras, J L; Eckhoff, D E; Cartner, S et al. (2000) Long-term functional islet mass and metabolic function after xenoislet transplantation in primates. Transplantation 69:195-201
Goldstein, D R; Chang, T; Sweeney, S D et al. (2000) A differential requirement for CD8+ donor cells in the augmentation of allograft survival by posttransplantation administration of donor spleen cells and donor bone marrow cells. Transplantation 70:1068-73
Thomas, F; Contreras, J; Ricordi, C et al. (1999) Reversal of naturally occurring insulinopenic diabetes and induction of isolated islet xenograft tolerance in a preclinical study. Transplant Proc 31:637-8
Asiedu, C; Meng, Y; Wang, W et al. (1999) Immunoregulatory role of CD8alpha in the veto effect. Transplantation 67:372-80
Thomas, F; Quarantillo, P; Contreras, J et al. (1999) Operational tolerance of long-surviving cardiac xenografts (LSCX) is related to modification of the graft-in-residence and not to induced tolerance in the recipient: studies in retransplanted LSCX. Transplant Proc 31:966-7
Contreras, J L; Eckhoff, D E; Cartner, S et al. (1999) Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients. Transplantation 68:215-9
Thomas, F; Pittman, K; Larkin, E et al. (1999) Characterization of xenograft resistance to autoimmune disease recurrence after pancreas islet transplantation. Transplant Proc 31:964-5

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