Defined Native Antigens and Immunity to Tuberculosis

Orme, Ian M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 1R01AI040488-01
• Application #: 2077256
• Study Section: Bacteriology and Mycology Subcommittee 2 (BM)
• Project Start: 1996-03-01
• Project End: 2001-02-28
• Budget Start: 1996-03-01
• Budget End: 1997-02-28
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Colorado State University-Fort Collins
• Department: Microbiology/Immun/Virology
• Type: Schools of Arts and Sciences
• DUNS #: 112617480
• City: Fort Collins
• State: CO
• Country: United States
• Zip Code: 80523

Publications

Ordway, Diane J; Orme, Ian M (2011) Animal models of mycobacteria infection. Curr Protoc Immunol Chapter 19:Unit19.5

Henao-Tamayo, Marcela I; Ordway, Diane J; Irwin, Scott M et al. (2010) Phenotypic definition of effector and memory T-lymphocyte subsets in mice chronically infected with Mycobacterium tuberculosis. Clin Vaccine Immunol 17:618-25

Ordway, Diane; Henao-Tamayo, Marcela; Harton, Marisa et al. (2007) The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation. J Immunol 179:522-31

Woolhiser, Lisa; Tamayo, Marcela Henao; Wang, Baolin et al. (2007) In vivo adaptation of the Wayne model of latent tuberculosis. Infect Immun 75:2621-5

Sambandamurthy, Vasan K; Derrick, Steven C; Hsu, Tsungda et al. (2006) Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis. Vaccine 24:6309-20

Junqueira-Kipnis, Ana Paula; Basaraba, Randall J; Gruppo, Veronica et al. (2006) Mycobacteria lacking the RD1 region do not induce necrosis in the lungs of mice lacking interferon-gamma. Immunology 119:224-31

Ordway, Diane; Harton, Marisa; Henao-Tamayo, Marcela et al. (2006) Enhanced macrophage activity in granulomatous lesions of immune mice challenged with Mycobacterium tuberculosis. J Immunol 176:4931-9

Park, Jae Seuk; Tamayo, Marcela Henao; Gonzalez-Juarrero, Mercedes et al. (2006) Virulent clinical isolates of Mycobacterium tuberculosis grow rapidly and induce cellular necrosis but minimal apoptosis in murine macrophages. J Leukoc Biol 79:80-6

Kipnis, Andre; Irwin, Scott; Izzo, Angelo A et al. (2005) Memory T lymphocytes generated by Mycobacterium bovis BCG vaccination reside within a CD4 CD44lo CD62 Ligandhi population. Infect Immun 73:7759-64

Irwin, Scott M; Izzo, Angelo A; Dow, Steven W et al. (2005) Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein. Infect Immun 73:5809-16