Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI041213-01
Application #
2077282
Study Section
Special Emphasis Panel (ZRG5-TMP (01))
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Pathology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Reller, Megan E; Dumler, J Stephen (2018) Development and Clinical Validation of a Multiplex Real-Time Quantitative PCR Assay for Human Infection by Anaplasma phagocytophilum and Ehrlichia chaffeensis. Trop Med Infect Dis 3:
Paris, Daniel H; Dumler, J Stephen (2016) State of the art of diagnosis of rickettsial diseases: the use of blood specimens for diagnosis of scrub typhus, spotted fever group rickettsiosis, and murine typhus. Curr Opin Infect Dis 29:433-9
Choi, Kyoung-Seong; Dumler, J Stephen (2013) Anaplasma phagocytophilum, interferon gamma production and Stat1 signaling. Microbiol Immunol 57:207-12
Dumler, J Stephen (2012) The biological basis of severe outcomes in Anaplasma phagocytophilum infection. FEMS Immunol Med Microbiol 64:13-20
Davies, R S; Madigan, J E; Hodzic, E et al. (2011) Dexamethasone-induced cytokine changes associated with diminished disease severity in horses infected with Anaplasma phagocytophilum. Clin Vaccine Immunol 18:1962-8
Grab, D J; Nyarko, E; Nikolskaia, O V et al. (2009) Human brain microvascular endothelial cell traversal by Borrelia burgdorferi requires calcium signaling. Clin Microbiol Infect 15:422-6
Zhang, Lijuan; Shan, Ailan; Mathew, Bobby et al. (2008) Rickettsial Seroepidemiology among farm workers, Tianjin, People's Republic of China. Emerg Infect Dis 14:938-40
Scorpio, Diana G; Leutenegger, Christian; Berger, Jeannine et al. (2008) Sequential analysis of Anaplasma phagocytophilum msp2 transcription in murine and equine models of human granulocytic anaplasmosis. Clin Vaccine Immunol 15:418-24
Grab, Dennis J; Nyarko, Elvis; Barat, Nicole C et al. (2007) Anaplasma phagocytophilum-Borrelia burgdorferi coinfection enhances chemokine, cytokine, and matrix metalloprotease expression by human brain microvascular endothelial cells. Clin Vaccine Immunol 14:1420-4
Dumler, J Stephen; Madigan, John E; Pusterla, Nicola et al. (2007) Ehrlichioses in humans: epidemiology, clinical presentation, diagnosis, and treatment. Clin Infect Dis 45 Suppl 1:S45-51

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