Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI041348-04A2
Application #
6348321
Study Section
AIDS and Related Research 8 (AARR)
Program Officer
Lambros, Chris
Project Start
1997-08-01
Project End
2004-05-31
Budget Start
2001-06-01
Budget End
2002-05-31
Support Year
4
Fiscal Year
2001
Total Cost
$449,819
Indirect Cost

  Institution

Name
Oklahoma State University Stillwater
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
City
Stillwater
State
OK
Country
United States
Zip Code
74078

  Publications

Bock, Ronnie A; Soulages, Jose L; Barrow, William W (2007) Substrate and inhibitor specificity of Mycobacterium avium dihydrofolate reductase. FEBS J 274:3286-98
Reynolds, Robert C; Campbell, Shiela R; Fairchild, Ralph G et al. (2007) Novel boron-containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation. J Med Chem 50:3283-9
Barrow, E W; Suling, W J; Seitz, L E et al. (2006) New antifolate inhibitors for Mycobacterium avium. Med Chem 2:505-10
Suling, W J; Seitz, L E; Reynolds, R C et al. (2005) New Mycobacterium avium antifolate shows synergistic effect when used in combination with dihydropteroate synthase inhibitors. Antimicrob Agents Chemother 49:4801-3
Barrow, W W (2001) Treatment of mycobacterial infections. Rev Sci Tech 20:55-70
Suling, W J; Seitz, L E; Pathak, V et al. (2000) Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase. Antimicrob Agents Chemother 44:2784-93
Suling, W J; Reynolds, R C; Barrow, E W et al. (1998) Susceptibilities of Mycobacterium tuberculosis and Mycobacterium avium complex to lipophilic deazapteridine derivatives, inhibitors of dihydrofolate reductase. J Antimicrob Chemother 42:811-5